Anti-BIN1 (Bridging integrator protein-1) 抗體說(shuō)明書(shū)

【資料簡(jiǎn)介】

 Anti-BIN1 (Bridging integrator protein-1) 抗體說(shuō)明書(shū) 

 Quantity size :   0.1ml (dilute with pH 7.4    0.01 M PBS or antibody diluent )

 

Background:   The identification and analysis of tumor suppressors is of major importance for improved diagnosis and treatment of tumors. Bin1 (Box-dependent myc interacting protein 1, also known as SH3P9, amphiphysin II and amphl/amphiphysin-like) is a novel protein that has features of a tumor suppressor. Bin1 interacts with and inhibits the oncogenic activity of the myc oncoprotein that has a major role in many human cancers. The loss of Bin1 may contribute to growth deregulation in cancer cells in carcinoma of the breast, colon, lung, cervix, prostate and liver. Bin1 also interacts with HCV NS through its SH3 domain. Also known as: Bridging integrator protein-1; Amphiphysin like protein; AMPH 2; AMPH2; Amphiphysin 2; Amphiphysin II; Amphiphysin like protein; amphiphysin-like; AMPHL; Box Dependant MYC Interacting Protein 1; Bridging Integrator 1; DKFZp547F068; MGC10367; MGC105358; Myc box dependent interacting protein 1; SH3P9.

 Anti-BIN1 (Bridging integrator protein-1) 抗體說(shuō)明書(shū) 

Specificity :    · anti-BIN1 is a rabbit polyclonal antibody unconjugated

                 · specific for BIN1 of human, rat and mouse

                 ·· epitope mapping in the middle of BIN1 of human, mouse and rat

origin

                 · use for western blotting, elisa, immunoprecipitation and

                   immunohistochemistry

 · Protein G affinity chromatography purification, purity :>95%

· Isotype: IgG

· mol wt: 77kDa

 

Application:     · Western blotting 1:100-500

                 ·Immunohistochemistry 1:100-500

                 · ELISA 1:500-1000

 · Optimal working dilutions must be determined by the end user.

Storage:     Store at –20 ºC for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20ºC. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody, the antibody is stable for at least two weeks at 2-4 ºC.

 

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Anti-BIN1 (Bridging integrator protein-1) 抗體說(shuō)明書(shū)