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武漢紐斯特生物科技有限公司
武漢紐斯特生物科技有限公司
Cdc42[26008][100µL]CatalogNumber:26008GeneSymbol:Cdc42Description:AntiCdc42MouseMonoclonalAntibodyBackground:SmallGTPasesareasuper-familyofcellularsignalingregulators
Cdc42 [26008]
[100 µL]
| Catalog Number: 26008 |
| Gene Symbol: Cdc42 |
| Description: Anti Cdc42 Mouse Monoclonal Antibody |
| Background: Small GTPases are a super-family of cellular signaling regulators. Cdc42 belongs to the Rho sub-family of GTPases that regulate cell motility, cell division, and gene transcription. GTP binding increases the activity of Cdc42, and the hydrolysis of GTP to GDP renders it inactive. GTP hydrolysis is aided by GTPase activating proteins (GAPs), while exchange of GDP for GTP is facilitated by guanine nucleotide exchange factors (GEFs). |
| Immunogen: Recombinant full length protein of Cdc42 |
| Applications: ELISA, WB, IHC |
| Recommended Dilutions: ELISA 1:100-1:5000, WB 1:100-1:2000 |
| Concentration: 1 mg/ml |
| Host: Mouse |
| Format: Liquid |
| Clonality: Monoclonal |
| Isotype: IgG |
| Purity: Purified from ascites |
| Storage buffer: |
| Preservative: no |
| Constituents: PBS (without Mg2+ ａnd Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
| Species Reactivity: Cdc42 antibody recognizes Cdc42 from vertebrates. |
| Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles |
| Download Datasheet: |
| Western blot: |
| Western blot analysis of Cdc42 proteins. MEF whole-cell lysate was used for western blot with the monoclonal anti-Cdc42 antibody (cat # 26008). |
| Related Products | |||
| Catalog# | Name | Size | Price |
| Cdc42 Activation Assay Kit | 20 assays | ￥6,800 | |
| Active Cdc42-GTP Monoclonal Antibody | 30 μL | ￥4,800 | |
| Anti-Cdc42 Mouse Monoclonal Antibody | 100 μL | ￥2800 | |
| Anti-Cdc42 Rabbit Polyclonal Antibody | 100 μL | ￥2600 | |
| Publications: |
| 1. PLoS Pathog. 2013 Jan;9(1):e1003142 |
| 2. Cytokine. 2012 Jan;57(1):158-68 |
| 3. European Journal of Cell Biology Volume 91, Issues 11–12, November–December 2012, Pages 978–987 |
| 4. J Cell Biol. 2012 Aug 20;198(4):677-93 |
| 5. Am J Physiol Lung Cell Mol Physiol. 2011 Jan;300(1):L32-42 |
| 6. Mol Cell Biol. 2011 Nov;31(22):4430-41 |
| 7. PLoS One. 2013 Jul 19;8(7):e70123 |
| 8. PLoS One. 2013 Sep 3;8(9):e73063 |
| 9. J Biol Chem. 2014 Jun 27;289(26):18347-59 |
| 10. United States Patent Application |
| 11. Molecular Pharmacology January 2014 vol. 85 no. 1 50-61 |
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