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diatheva生物科技公司成立于2002年,總部位于意大利。是一家以使研究工業(yè)產(chǎn)品的私人研究機(jī)構(gòu)。diatheva集中開發(fā)在該領(lǐng)域的研究和治療應(yīng)用:癌癥,微生物感染和藥理學(xué)。新產(chǎn)品的生產(chǎn)和銷售(抗體,重組蛋白,免疫和SNP檢測(cè)試劑盒)的診斷,在該領(lǐng)域的研究和治療應(yīng)用:癌癥,微生物感染和藥理學(xué)。diatheva有GMP授權(quán)設(shè)施設(shè)計(jì)的臨床前和臨床試驗(yàn)的研究與對(duì)艾滋病病毒和其他微生物病原體的免疫原,特別強(qiáng)調(diào)新原料藥生產(chǎn)。diatheva是意大利能夠*個(gè)設(shè)施提供GMP服務(wù)點(diǎn)播。
The PBRT kit is intended for molecular typing of plasmid conferring drug resistance in Enterobacteriaceae.
The epidemiology of resistance plasmids is a major issue for the description of antimicrobial resistance diffusion. Plasmids can be categorized in families on the basis of their phylogenetic relatedness. The first classification scheme was based on the stability of plasmids during conjugation, a phenomenon called plasmid incompatibility (Inc). Incompatibility groups were defined as the inability of related plasmids to be propagated stably in the same cell line, thus only compatible plasmids can be rescued in transconjugants (Datta and Hughes, 1983; Inc groups are defined as reported by the Plasmid Section of the National Collection of Type Culture, Colindale London, UK). The Inc methodology cannot be easily applied to a large number of strains and its use has been limited by the laborious and time-consuming work required. The molecular identification and classification of plasmids by PCR is currently possible and it is based on the detection of plasmid replication controls (replicons), namely the portion of large, naturally occurring plasmids encoding the replicase gene (rep) and cis-acting regulatory elements, controlling plasmid DNA replication and copy number.
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