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聯(lián)系我時,請告知來自 環(huán)保在線博研生物強(qiáng)烈*“Anti-HES4抗體,轉(zhuǎn)錄因子HES4抗體說明",品質(zhì)保障,*,提供,實驗無結(jié)果可免費退換?。?/p>
Anti-HES4抗體,轉(zhuǎn)錄因子HES4抗體說明介紹:The Drosophila hairy and Enhancer of split genes encode basic helix-loop-helix (bHLH) transcriptional repressors that function in the Notch signaling pathway and control segmentation and neural development during embryogenesis. The mammalian homologues of Drosophila hairy and Enhancer of split are the HES gene family members, HES1-6, which also encode bHLH transcriptional repressors that regulate myogenesis and neurogenesis. The HES family members form a complex with TLE, the mammalian homologue of Groucho, and this interaction is mediated by the carboxy terminal WRPW motif of the HES proteins. The HES/TLE complex functions by directly binding to DNA, instead of interfering with activator proteins. Most HES family members, including HES1 and HES5, preferentially bind to the N box (CACNAG) as opposed to the E box (CANNTG). HES2 binds to both N and E box sites, while HES6 does not bind DNA. Rather, HES6 inhibits HES1 activity, thereby promoting transcription. HES1 and HES2 are expressed in a variety of adult and embryonic tissues. HES3 is expressed exclusively in cerebellar Purkinje cells, and HES5 is found solely in the nervous system. HES6 is produced in brain as well as in the limb buds of developing embryos.
相關(guān)的標(biāo)記有:Alexa Fluor 350 標(biāo)記、Alexa Fluor 488 標(biāo)記、Alexa Fluor 555 標(biāo)記、Alexa Fluor 647 標(biāo)記、AP標(biāo)記、APC標(biāo)記、Biotin標(biāo)記、Cy3標(biāo)記、Cy5標(biāo)記、Cy5.5標(biāo)記、Cy7標(biāo)記、FITC標(biāo)記、Gold標(biāo)記、HRP標(biāo)記、PE標(biāo)記、PE-Cy3標(biāo)記、PE-CY5標(biāo)記、PE-CY5.5標(biāo)記、PE-CY7標(biāo)記、RBITC標(biāo)記
保存條件:Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹:
產(chǎn)品名稱:Anti-HES4抗體,轉(zhuǎn)錄因子HES4抗體說明
產(chǎn)品編號:BYK-11567R
英文名稱 HES4
中文名稱 轉(zhuǎn)錄因子HES4抗體
別 名 bHLH factor Hes4; Hairy and enhancer of split 4; Transcription factor HES 4; HES4_HUMAN.
研究領(lǐng)域 神經(jīng)生物學(xué) 轉(zhuǎn)錄調(diào)節(jié)因子
分 子 量 24kDa
細(xì)胞定位 細(xì)胞核
產(chǎn)品價格:詢價(電詢或客服)
抗體來源:本公司抗體有兔來源和鼠來源等
克隆類型:兔來源為多抗,鼠來源為單抗
產(chǎn)品類型:一抗
產(chǎn)品用途:科研實驗
性 狀: Lyophilized or Liquid
濃 度: 1mg/1ml
亞 型: IgG
貯 存: 貯存于-20℃.
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