Anti-hHR23A抗體,紫外切除修復蛋白RAD23A抗體免疫實驗

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博研生物強烈*“Anti-hHR23A抗體,紫外切除修復蛋白RAD23A抗體免疫實驗"，品質(zhì)保障，*，提供，實驗無結(jié)果可免費退換?。?/p>

詳細介紹

Anti-hHR23A抗體,紫外切除修復蛋白RAD23A抗體免疫實驗介紹：Mammalian cells express two Rad23 (genome repair protein) homologs, Rad23A (also designated HR23A) and Rad23B (also designated HR23B). In typical cells, mouse Rad23B is approximay ten times more abundant than mouse Rad23A. Endogenous XPC (xeroderma pigmentosum C protein) located in wildtype mouse embryonic fibroblasts is relatively stable; its steady-state level and stability appear to be significantly reduced by a targeted interruption of the mouse Rad23B gene, but not by that of mouse Rad23A. Loss of both mouse Rad23 genes causes a strong further reduction of the XPC protein level. The RAD23 genes (RAD23A and RAD23B), which encode the human Rad23 proteins, are crucial for excision-repair of UV-damaged DNA. RAD23 genes resemble the other DNA repair genes, RAD2, RAD6, RAD7, RAD18 and RAD54, all of which also exhibit increased transcription in response to DNA damage and during meiosis. Rad23 is a nuclear protein containing an ubiquitin-like domain required for biological functions. The protein, which is highly conserved, is involved in nucleotide excision repair (NER) that associates with the proteasome via its N-terminus. The C-terminal ubiquitin-associated domain of Rad23 is evolutionarily conserved from yeast to humans. Rad23 may also act as a regulator for the activity of the 26S Proteasome.

相關的標記有：Alexa Fluor 350 標記、Alexa Fluor 488 標記、Alexa Fluor 555 標記、Alexa Fluor 647 標記、AP標記、APC標記、Biotin標記、Cy3標記、Cy5標記、Cy5.5標記、Cy7標記、FITC標記、Gold標記、HRP標記、PE標記、PE-Cy3標記、PE-CY5標記、PE-CY5.5標記、PE-CY7標記、RBITC標記

保存條件：Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

產(chǎn)品介紹：

產(chǎn)品名稱：Anti-hHR23A抗體,紫外切除修復蛋白RAD23A抗體免疫實驗
產(chǎn)品編號：BYK-15481R

英文名稱 hHR23A
中文名稱紫外切除修復蛋白RAD23A抗體
別名 hHR 23A; HR23A; R23A; MGC111083; RAD 23a; RAD23 homolog A; RAD23 yeast homolog A; RAD23a; RD23A_HUMAN; UV excision repair protein RAD23; UV excision repair protein RAD23 homolog A.
研究領域細胞生物免疫學表觀遺傳學
分子量 40kDa
細胞定位細胞核

產(chǎn)品價格：詢價(電詢或客服)
抗體來源：本公司抗體有兔來源和鼠來源等
克隆類型：兔來源為多抗，鼠來源為單抗
產(chǎn)品類型：一抗
產(chǎn)品用途：科研實驗
性狀： Lyophilized or Liquid
濃度： 1mg/1ml
亞型： IgG
貯存：貯存于-20℃.

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